November 6 2024
News – Curated by Amanda Scott, Alias Group Creative
Nanodiscs: What Are They and How Are They Shaping the Future of Medicine?
Nanodiscs are synthetic phospholipid particles with a distinct morphology and size that enhance their efficiency in drug delivery applications.1 First developed by Sligar et al. in the early 2000s, these model membrane systems measure around 10 [...]
New Discovery Reveals How Ovarian Cancer Starves Immune Cells
Researchers discovered that ovarian tumors hinder T cells’ energy supply by trapping a key protein, blocking lipid uptake. A new approach to reprogram T cells could enhance immunotherapy for aggressive cancers. Researchers at Weill Cornell [...]
Innovative Drug-Design Strategies to Overcome Antibacterial Resistance
Antibacterial resistance occurs when antibiotics fail to treat bacterial infections. This incidence is considered one of the top global health threats, stemming from the misuse or overuse of antibiotics in humans and animals.1 The [...]
Team introduces a cost-effective method to redesign search engines for AI
The internet search engine of the future will be powered by artificial intelligence. One can already choose from a host of AI-powered or AI-enhanced search engines—though their reliability often still leaves much to be [...]
Experiments demonstrate precise delivery of nanoparticles to lung
In recent years, bio-medical engineers have been developing promising techniques that could help diagnose diseases or precisely target specific regions inside the human body. Among these promising therapeutic strategies are methods that rely on [...]
What is Lassa fever? Everything to know about Ebola-like virus
Lassa fever has reached the US for the first time in a decade, in a case that has surprised health officials. The middle-aged patient in Iowa, who was not identified, died a 'short time' after being hospitalized [...]
Harvard Study Links Popular Plastic Ingredient to DNA Damage
Phthalate affects egg formation in C. elegans, resulting in abnormal chromosome numbers. A recent study conducted on roundworms has discovered that a common plastic ingredient can cause DNA strand breaks, leading to egg cells with an abnormal [...]
New research finds that subtle eye movements optimize vision
Our ability to see starts with the light-sensitive photoreceptor cells in our eyes. A specific region of the retina, termed fovea, is responsible for sharp vision. Here, the color-sensitive cone photoreceptors allow us to [...]
Scientists Were Wrong: Plants Absorb 31% More CO2 Than Previously Thought
New research shows plants absorb 31% more CO2 than previously estimated, raising the global GPP to 157 petagrams per year. Using carbonyl sulfide as a proxy for photosynthesis, this study highlights tropical rainforests’ critical role [...]
Doctors test first mRNA vaccine against norovirus
According to the Robert Koch Institute (RKI), the norovirus, which is widespread worldwide, is the cause of a large proportion of gastrointestinal infections. Those who catch the virus suffer from nausea, diarrhea and vomiting. [...]
Study reveals resistance of Pseudomonas aeruginosa to common cleaning agents
A new study reveals widespread resistance of a major bacterial pathogen to the active ingredients in cleaning agents commonly used in hospitals and homes. The American Chemical Society Infectious Diseases published the research, led [...]
AI’s Next Frontier: System 0 and the Future of Human Thought
“System 0” represents an emerging cognitive tool powered by AI that works alongside human intuition and analysis to enhance cognitive abilities. This new system promises to support complex decision-making and problem-solving but requires careful [...]
The Global Nanomedicine Market: Key Players and Emerging Technologies in Healthcare
This article provides an overview of the global nanomedicine market, highlighting key players, emerging technologies, and the challenges and opportunities that influence its growth and commercialization in the healthcare sector. Nanomedicines are nanotechnology-based drug products [...]
Scientists Have Discovered Toxic “Forever Chemicals” in Bottled Water
Scientists have found toxic PFAS in drinking water samples from around the world, with higher levels in tap water from China compared to the UK. Boiling water or using a filtration jug can reduce [...]
Urban Microbes Are Eating Disinfectants – Are We Fueling a New Health Threat?
New research reveals that microbes in urban environments are evolving to withstand the very cleaning agents designed to eliminate them. The study also uncovers new strains in Hong Kong, previously only found in the [...]
Startling Study Shows High-Potency Cannabis Alters DNA
The study shows that frequent use of high-potency cannabis alters DNA, affecting genes related to energy and immune function. These changes differ between those with and without psychosis, suggesting cannabis use could influence mental health through biological [...]
Frank Boehm (Founder, NanoAppsMedical Inc.) interview
Dr. Bob Hieronimus hosted an in depth two-hour long interview with NanoApps Medical Founder Frank Boehm, who discussed his first book, and his three new books in progress. Among the topics of discussion were his startup NanoApps Medical, the challenges of securing funding for nanomedical research, and how the EU is standing out due to its exciting and aggressive program of investing heavily in innovation and the future.
Frank then articulated his vision of how synergies between nanotechnology, nanomedicine, and AI may culminate (in ~10-20 years time) in what he refers to as Global Health Care Equivalency (GHCE), which will be driven by Molecular Manufacturing (MM). Further topics included nanomedicine in space applications, and how a brain/cloud interface might some day emerge through nanomedical robotics.
Nanomedical Device and Systems Design: Challenges, Possibilities, Visions by Frank Boehm
Nanomedical Device and Systems Design: Challenges, Possibilities, Visions by Frank Boehm of NanoApps Medical Inc. serves as a preliminary guide toward the inspiration of specific investigative pathways that may lead to meaningful discourse and significant advances in nanomedicine/nanotechnology.
This volume considers the potential of future innovations that will involve nanomedical devices and systems. It endeavors to explore remarkable possibilities spanning medical diagnostics, therapeutics, and other advancements that may be enabled within this discipline.
In particular, this book investigates just how nanomedical diagnostic and therapeutic devices and systems might ultimately be designed and engineered to accurately diagnose and eradicate pathogens, toxins, and myriad disease states.
Frank Boehm contributes to ‘The Physics of the Mind and Brain Disorders’ – Now available from Springer Press
Frank Boehm (NanoApps Medical CEO) and Angelika Domschke contributed the chapter : “Application of a Conceptual Nanomedical Platform to Facilitate the Mapping of the Human Brain: Survey of Cognitive Functions and Implications”.
The book covers recent advances in the understanding of brain structure, function and disorders based on the fundamental principles of physics. It covers a broad range of physical phenomena occurring in the brain circuits for perception, cognition, emotion and action, representing the building blocks of the mind.
It provides novel insights into the devastating brain disorders of the mind such as schizophrenia, dementia, autism, aging or addictions, as well as into the new devices for brain repair.
Potential Nanomedical Countermeasures to Mitigate the Effects of Space on Humans
Incremental progress has been made on several fronts that may employ nanomedical strategies, to potentially counteract the deleterious effects of galactic cosmic rays and microgravity on human physiology. The implementation of these strategies and the enhancement of their preventative, diagnostic, or therapeutic effects for future orbital, planetary, and deep space missions might be enabled via diverse and potent synergies between unique nanomedical applications of nanomaterials and nanotechnologies.
NanoApps Medical, Inc. Aiming to Develop Nanobiosensor for Malaria, Ebola, and Zika
NanoApps Medical, Inc. (Vancouver, Canada) is working to develop a point of care diagnostic nanobiosensor platform for the detection of Malaria via saliva samples, which may be reconfigured to detect Ebola, and Zika. The use of this nanobiosensor will be far less invasive and safer than through the extraction of blood samples, while conveying more rapid results.
The current gold standard for the detection of Malaria is blood smear microscopy, the results of which may take from many hours to several days to determine. This test also has the requirements of technical expertise in blood sample preparation, and a trained microscopist. Hence, the proposed nanobiosensor would be a significant improvement in terms of expediting and simplifying the diagnosis of Malaria, Ebola, and Zika in that it would be easy to administer, and provide rapid and clearly understandable results.
Frank Boehm represents Alias Group Creative in North America
From Alias Group Creative:
To better serve our new Aerospace, Nanotechnology, and Nanomedicine clients we are pleased to engage Frank Boehm of Vancouver Canada to represent Alias in North America.
A true entrepreneur and author of the respected reference book: Nanomedical Device and Systems Design: Challenges, Possibilities, Visions, Frank is the CEO of NanoApps Medical Inc.
Nanotechnology, Nanomedicine, and AI: Toward the Dream of Global Health Care Equivalency
Synergies between nanotechnology, nanomedicine, and AI may enable this vision on a global scale. Progress toward this goal will be incremental, with each successive wave of nanomedical technologies being more advanced than the previous wave. The tipping point will arrive with the emergence of Molecular Manufacturing (MM), which will make possible the economical fabrication of the types of advanced autonomous nanomedical devices that are described in Frank’s initial book: Nanomedical Device and Systems Design: Challenges, Possibilities, Visions
NanoApps Medical keenly recognizes that such a massive undertaking on a global scale will require intense and high spirited collaboration with like minded individuals, research labs, institutions, organizations, and government agencies worldwide for its realization. It will also require significant resources and time.
NanoApps Medical Inc. Near-Term Projects
NanoApps Medical is aiming to investigate the possibility that superparamagnetic nanoparticles (SPIONs) and other classes of nanoparticles (e.g., gold coated nanoshells) might have the capacity to target cancerous tumors, metastasizing cancer cells, pathogens, etc. to deactivate/eliminate them via hypothermia.
NanoMedicine and Human Spaceflight
Future nanomedical devices and systems will have strong potential to enable a broad range of aerospace and space applications. With further dimensional reductions in conjunction with the increased capabilities of nanoelectronics and artificial intelligence (AI), nanomedicine may facilitate the development of a wide array of advanced nanomedical diagnostic and therapeutic capabilities dedicated to the health and well being of future astronauts and space pioneers, the inhabitants of future Lunar and Mars colonies, and deep space explorers.
Ocular and Cellular Anomalies
Microgravity induced ophthalmic anomalies were observed by Mader et al in seven astronauts who were involved in long-duration (six month) space missions to the ISS. An additional 300 astronauts were asked to complete a questionnaire in regard to in-flight vision changes. For the seven astronauts under study, the ophthalmic results indicated disk edema (in five), globe flattening (in five), choroidal folds (in five), cotton wool spots (in three), nerve fiber layer thickening (in six), decreased near-vision (in six). Further, optic nerve sheath distension and tortuous optic nerves were observed.
Of the 300 questionnaire respondents, 60% of the astronauts who were engaged in long duration missions reported experiencing degradation in both their near and distance vision; these conditions persisted for years postflight for some individuals.
Cardiac Function and Muscle Atrophy
In 2004, NASA released its Bioastronautics Critical Path Roadmap (BCPR), with an aim to “establish tolerance limits to the space environment and develop countermeasures to overcome these problems.” The BCPR listed close to 50 space-related medical risk factors, which included those associated with the potential for serious cardiac dysrhythmias (from unknown causes) that may lead to hypotension (low blood pressure) and syncope (fainting). Further, significant cardiac rhythm issues (e.g., ventricular tachycardia – rapid heartbeat), linked with altered cardiac electrical activity and stability were reported for a number of cases during a MIR mission.
Degraded cardiac and vascular functionality, as well as decreased cardiac mass can result from both short and long duration spaceflight.