Summary: A new study demonstrates that primary brain tumors (gliomas) are particularly receptive to targeted drug delivery using focused ultrasound (FUS) combined with microbubbles. The team developed a high-resolution MRI protocol to track blood-brain barrier (BBB) opening and molecular transport inside the tumor microenvironment. The research allays long-standing clinical concerns that mutated tumor vasculature would [...]
AI tools are becoming increasingly common in early drug discovery, allowing scientists to analyse data and navigate large volumes of research. However, according to Dr Raminderpal Singh, turning that potential into consistent scientific workflows is far from straightforward. Artificial intelligence (AI) is becoming an increasingly prominent part of drug discovery, particularly in early-stage research where [...]
From the preface of the book Global Health Care Equivalency in the Age of Nanotechnology, Nanomedicine and Artificial Intelligence, Edited by Frank Boehm: Since the publication of my first book (Nanomedical Device and Systems Design: Challenges, Possibilities, Visions – CRC Press, 2013), it became increasingly evident that synergies between the concurrently rapid advances in [...]
Health-related updates reveal financial adjustments by Universal Health Services due to Medicaid reimbursement uncertainties, significant pollution-linked health concerns from French-British oil firm Perenco in Congo, drug trial setbacks, potential restructuring at major medical firms, and escalations in infectious disease outbreaks, highlighting ongoing challenges and developments in the healthcare sector. Key Takeaways AI Summary Universal [...]
Scientists have identified a brain protein that may help Alzheimer’s spread, revealing a potential new target for slowing the disease’s progression. Alzheimer’s disease is closely linked to the accumulation of a toxic form of the protein Tau inside the brain. As Tau damage reaches additional brain regions, more neurons are harmed, symptoms intensify, and the disease [...]
Introduction Growing evidence suggests that disruptions in immune function may play an important role in the development and progression of psychiatric disorders. However, immune mechanisms probably contribute more strongly in some patients than others, and observed abnormalities may represent causal factors, consequences of illness or treatment, or shared confounding influences.2,3 Inflammation, neuroimmune signaling, and [...]
Controlled electrical discharges could enable triboelectric nanogenerators to achieve higher peak currents, extending nano-enabled energy harvesting into chemical processing and self-powered sensing. Paper: Electrostatic discharge as a breakthrough strategy for triboelectric nanogenerators. A new review published in the journal Communications Materials explores how electrostatic discharge (ESD) can help address long-standing performance limitations in triboelectric nanogenerators (TENGs). The [...]
Researchers at the University of Geneva are combing through collections of approved drugs to find new therapies for rare diseases – with some success. This approach is gaining traction around the world, while pharmaceutical companies' interest in developing drugs is waning. Five years ago, Vladimir Katanaev's laboratory at the University of Geneva made a [...]
By pairing robust artificial enzymes with highly selective aptamers, nanozyme aptasensors could help detect disease biomarkers, pathogens, and contaminants faster, but the review shows that real-world deployment still depends on overcoming matrix interference, biofouling, and manufacturing challenges. A recent review accepted as an 'Article in Press' in the journal npj Biosensing explored how synthetic enzyme-like nanomaterials, [...]
Aneuroprosthetic system has allowed a man with paralysis to grasp and lift objects and feel touch again. The device helped 42-year-old Keith Thomas of Massapequa, New York, who was paralyzed from the chest down after a diving accident in 2020. After the accident, he couldn’t lift his hands to his face and had no [...]
