The Food and Drug Administration (FDA) approved on Wednesday a drug that could extend the survival of those with metastatic pancreatic cancer. The drug, called daraxonrasib, will be sold under the brand name Rasonque from Revolution Medicines. The daily pill targets multiple forms of a protein called RAS, which is a main driver of [...]
Machine learning identifies the likely “initiator” and enables new predictions about DNA mutations that can cause disease. Every human cell depends on tens of thousands of genes being switched on at the right time and in the right amount. Specialized stretches of DNA coordinate this activity, ultimately directing the production of enzymes, hormones, proteins, [...]
Pope Leo called for international action to address the Ebola outbreak in the Democratic Republic of Congo. The epidemic has claimed over 2,500 lives and is the nation's largest recorded outbreak. The Pope emphasized involving local communities in prevention efforts to curb the disease's spread. On Sunday, Pope Leo made a fervent appeal for [...]
Hantavirus. Ebola. West Nile. Measles. And, of course, cyclospora — that stomach parasite making people miserable across the country. Americans have plenty to worry about this summer. But remember COVID-19? It may not be surprising that many people may have almost forgotten about COVID. Unfortunately, COVID hasn't forgotten about us. "We're now in the [...]
Swinburne researchers have discovered how broccoli could help treat an extremely rare and incurable disease that affects only about 200 Australians. A naturally occurring compound in broccoli is being investigated as a possible treatment for Friedreich ataxia, a rare nervous system disease. Research from Swinburne suggests the compound can act on biological processes involved [...]
FcRn plays a central role in regulating the half-life of IgG antibodies and albumin, making it a critical target in both antibody engineering and autoimmune disease therapy. This article explores the biology of FcRn, the use of HMEC-1 cells for measuring FcRn-mediated IgG recycling, and the assays used to support the development of next-generation [...]
It’s Congo’s 17th outbreak, with a toll that has eclipsed that of the country’s 2018-2020 outbreak when 2,299 deaths out of 3,481 cases were recorded. The latest data shows 101 new cases and 33 deaths reported in the previous 24 hours. Over 1,000 people have recovered, while 730 remain in hospitals or isolation. The [...]
At a moment when AI is forcing a fundamental rethink of how work gets done, the life sciences industry is grappling with a deeper question: what role should human creativity play in an increasingly automated world? For Mike Guarino, CEO of EVERSANA INTOUCH, the answer lies not in replacement, but in amplification. He describes [...]
A simple blood test that detects chemical changes in DNA identified more than 90% of stage 2-4 lung cancers in an early study, without relying on costly DNA sequencing. Researchers at Tel Aviv University and collaborating medical centers have developed a blood test for lung cancer that analyzes chemical patterns on fragments of DNA circulating in [...]
Professor Joseph C. Wu of Stanford University explains how stem cells, human-relevant models and AI are helping researchers predict which drug candidates are most likely to succeed before clinical trials. Researchers now have access to technologies that were unimaginable mere decades ago, from genome editing to patient-derived organoids. Despite these advances, many promising drug candidates [...]
