Treating cancer with combinations of drugs can be more effective than using a single drug. However, figuring out the optimal combination of drugs, and making sure that all of the drugs reach the right place, can be challenging. To help address those challenges, MIT chemists have designed a bottlebrush-shaped nanoparticle that can be loaded [...]
By one unique metric, we could approach technological singularity by the end of this decade, if not sooner. A translation company developed a metric, Time to Edit (TTE), to calculate the time it takes for professional human editors to fix AI-generated translations compared to human ones. This may help quantify the speed toward singularity. An AI that [...]
Phase transition in early universe changes strength of interaction between dark and normal matter. Dark matter remains one of the greatest mysteries of modern physics. It is clear that it must exist, because without dark matter, for example, the motion of galaxies cannot be explained. But it has never been possible to detect dark [...]
Summary: Researchers have developed a new family of nano-scale capsules capable of carrying CRISPR gene editing tools to different organs of the body before harmlessly dissolving. The capsules were able to enter the brains of mice and successfully edit a gene associated with Alzheimer’s disease. Source: University of Wisconsin-Madison Gene therapies have the potential to treat [...]
An enzyme that defends human cells against viruses can help drive cancer evolution towards greater malignancy by causing myriad mutations in cancer cells, according to a study led by investigators at Weill Cornell Medicine. The finding suggests that the enzyme may be a potential target for future cancer treatments. In the new study, published recently [...]
Using a mouse model, Japanese researchers unleash the likely mechanism of action of Actinidia arguta (sarunashi) juice on lung cancer development. Lung cancer is a leading cause of death in Japan and across the globe. Among all the cancers, lung cancer has one of the lowest five-year survival rates. Smoking tobacco and using tobacco-based [...]
When used as wearable medical devices, stretchy, flexible gas sensors can identify health conditions or issues by detecting oxygen or carbon dioxide levels in the breath or sweat. They also are useful for monitoring air quality in indoor or outdoor environments by detecting gas, biomolecules and chemicals. But manufacturing the devices, which are created [...]
Novel drugs, such as vaccines against covid-19, among others, are based on drug transport using nanoparticles. Whether this drug transport is negatively influenced by an accumulation of blood proteins on the nanoparticle’s surface was not clarified for a long time. Scientists at the Max Planck Institute for Polymer Research have now followed the path [...]
Imagine it is 2030. Doctors in a regional hospital in country X note an expanding cluster of individuals with severe respiratory disease. Rapid whole-genome sequencing identifies the disease-causing agent as a novel coronavirus. Epidemiological investigations suggest the virus is highly infectious, with most initial cases requiring hospitalisation. The episode bears a striking resemblance to [...]
A predictive model has been developed that enables researchers to encode instructions for cells to execute. Scientists at the University of California, San Francisco (UCSF) and IBM Research have created a virtual library of thousands of “command sentences” for cells using machine learning. These “sentences” are based on combinations of “words” that direct engineered immune cells to find [...]
