High-grade serous ovarian cancer (HGSOC) is among the deadliest human cancers and its prognosis remains extremely poor. An article published in Advanced Science explored the self-therapeutic properties of gold nanoparticles to identify a molecular axis that fosters the growth of HGSOC. The gold nanoparticles injected intravenously or intraperitoneally in single or multiple doses over two weeks [...]
Antimicrobial peptides (AMPs) have a broad spectrum of antimicrobial activity and lyse microbial cells by interaction with biomembranes, offering great potential in designing new therapeutics. The antimicrobial resistance (AMR) caused due to overuse of antibiotics can be circumvented by using AMPs as alternatives to antibiotics. The rod-shaped chitosan nanocrystals are polysaccharide-based nanomaterials obtained by [...]
Tumor cells are notoriously good at evading the human immune system; they put up physical walls, wear disguises and handcuff the immune system with molecular tricks. Now, UC San Francisco researchers have developed a drug that overcomes some of these barriers, marking cancer cells for destruction by the immune system. The new therapy, described [...]
Hyperspectral microscopy is an advanced visualization technique that combines hyperspectral imaging with state-of-the-art optics and computer software to enable rapid identification of nanomaterials. Since hyperspectral datacubes are large, their acquisition is complicated and time-consuming. Despite the efficiency of spectral scanning in acquiring hyperspectral datacubes, this technique cannot be extended to large numbers of spectral [...]
Malignant brain tumors are cancerous growth in the brain with the possibility of spreading to other parts of the central nervous system (CNS). Brain tumors are highly invasive and have devastating consequences, poor prognosis, and low survival rates. Recently, the noninvasive near-infrared fluorescence and photoacoustic imaging techniques have demonstrated a bright scope in brain [...]
An ultrathin invention could make future computing, sensing and encryption technologies remarkably smaller and more powerful by helping scientists control a strange but useful phenomenon of quantum mechanics, according to new research recently published in the journal Science ("Resonant metasurfaces for generating complex quantum states"). Scientists at Sandia National Laboratories and the Max Planck Institute for [...]
Methacrylate-based materials are often used in bone cement and dental resins. However, they have high failure rates as they undergo damage within ten years, impacting the quality of patient’s life and increasing healthcare costs. Although replacing methacrylate-based materials with self-healing resins and bone cement could increase lifespan, reduce costs, and enhance patient outcomes, the [...]
Early diagnosis of an infectious viral disease can help the patients and health care professionals monitor the outbreaks accurately and provide treatment at the early stage of a disease, avoiding any detrimental consequences. The accuracy of information is essential while monitoring such diseases to prevent any possible pandemics. An article published in the journal ACS [...]
Researchers at Duke University have developed a unique type of nanoparticle called a “nanorattle” that greatly enhances light emitted from within its outer shell. Loaded with light scattering dyes called Raman reporters commonly used to detect biomarkers of disease in organic samples, the approach can amplify and detect signals from separate types of nanoprobes [...]
A household microwave oven modified by a Cornell Engineering professor is helping to cook up the next generation of cellphones, computers and other electronics after the invention was shown to overcome a major challenge faced by the semiconductor industry. The research is detailed in a paper in Applied Physics Letters ("Efficient and stable activation by microwave [...]
