Summary: New research reveals that aging isn’t just a local cellular process—it can spread throughout the body via the bloodstream. A redox-sensitive protein called ReHMGB1, secreted by senescent cells, was found to trigger aging features in distant tissues, impairing regeneration and muscle function. Blocking ReHMGB1 with antibodies in mice reduced cellular aging markers and improved [...]
Imagine a stadium packed with 75,000 fans, all wearing green and white jerseys—except one person in a solid green shirt. Finding that person would be tough. That's how hard it is for scientists to find disease markers—called biomarkers—in the blood. And instead of one stadium, researchers must search through the equivalent of 100,000 stadiums [...]
Fungicides used in agriculture have been linked to an increase in resistance to antifungal drugs in both humans and animals. Fungal infections are on the rise, and two UC Davis infectious disease experts, Dr. George Thompson and Dr. Angel Desai, are sounding the alarm. In a recent commentary published in the New England Journal of Medicine, they [...]
A collaborative team from Penn Medicine and Penn Engineering has uncovered the mathematical principles behind a 500-million-year-old protein network that determines whether foreign materials are recognized as friend or foe. How does your body tell the difference between friendly visitors, like medications and medical devices, and harmful invaders such as viruses and other infectious [...]
A team of international researchers led by scientists at City of Hope provides the most thorough account yet of an elusive target for cancer treatment. Published in Science Advances, the study suggests a complex signaling process involving paxillin, a focal adhesion protein that acts as a hub to connect with other proteins, may be vulnerable [...]
Eye diseases are becoming more common. In 2020, over 250 million people had mild vision problems, and 295 million experienced moderate to severe ocular conditions. In response, researchers are turning to nanotechnology and nanomaterials—tools that are transforming how we approach eye health. These technologies are improving how drugs are delivered to the eye and supporting new developments [...]
Researchers found that natural polymers derived from okra and fenugreek are highly effective at removing microplastics from water. The same sticky substances that make okra slimy and give fenugreek its gel-like texture could help clean our water in a big way. Scientists have discovered that these natural plant extracts are surprisingly good at trapping [...]
A new genetic study shows that just one extra cup of instant coffee a day could significantly increase your risk of developing dry AMD, shedding fresh light on how our daily beverage choices may shape long-term eye health. In a recent study published in the journal Food Science & Nutrition, researchers utilized an extensive genomic [...]
A patch containing tens of millions of microscopic nanoneedles could soon replace traditional biopsies, scientists have found. The patch offers a painless and less invasive alternative for millions of patients worldwide who undergo biopsies each year to detect and monitor diseases like cancer and Alzheimer's. The research is published in Nature Nanotechnology. Biopsies are among [...]
Scientists have discovered a unique class of small antibodies that are strongly protective against a wide range of SARS coronaviruses, including SARS-CoV-1 and numerous early and recent SARS-CoV-2 variants. The unique antibodies target an essential highly conserved site at the base of the virus's spike protein, effectively clamping it shut and preventing the virus [...]
