Several antivirals, including remdesivir, Paxlovid, molnupiravir, and monoclonal antibodies like tixagevimab and cilgavimab, have been repurposed to treat the coronavirus disease 2019 (COVID-19) or received emergency use authorization (EUA). Antimalarial and antiparasitic drugs like ivermectin, hydroxychloroquine, and chloroquine have also been investigated for their potential activity against the severe acute respiratory syndrome coronavirus 2 [...]
Melissa, a 30-year-old educator, came to the emergency department with a sudden onset of double vision. She had not been in an accident or suffered any trauma and had never experienced this symptom before. However, she noted that a few months earlier, the vision in one of her eyes had become blurred and then [...]
Autoimmune diseases are widespread and notoriously difficult to treat. In part, this is because why the immune system attacks its own tissues in patients with these conditions remains poorly understood. In a study recently published in Cell, researchers from Osaka University have revealed that the body's own proteins with unusual structure trigger immune cells to [...]
In a recent study published in the journal PLOS ONE, researchers conducted a systematic review and meta-analyzed data on the impact of coronavirus disease 2019 (COVID-19) on male reproductive hormones and semen variables to determine whether severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections had an adverse impact on male fertility. Background The etiological agent [...]
New method uses patient-derived neurons to effectively simulate late-onset Alzheimer’s and identify possible treatments. Researchers at Washington University School of Medicine in St. Louis have created a technique to explore the impact of aging on Alzheimer’s disease development. This new method allows for the study of aged neurons in the laboratory without requiring a brain biopsy, which could [...]
Teenage girls' brains may have prematurely aged by up to four years during the Covid pandemic, an American study suggests. Adolescent boys weren't immune either with their brain's also showing signs of undue wear and tear, albeit by only one-and-a-half years. Experts suggested the difference was due to lockdown's social restrictions having a disproportionate impact [...]
Routine lab tests are not reliable for diagnosing Long COVID, according to a new study. The research found that no clinical lab values could serve as biomarkers, highlighting the need to focus on symptoms for diagnosis. A new study found that most routine laboratory tests are not reliable for diagnosing Long COVID, also known [...]
Researchers have created nanoscale robots which could be used to manage bleeds in the brain caused by aneurysms. The development could enable precise, relatively low-risk treatment of brain aneurysms, which cause around 500,000 deaths globally each year. The medical condition—a blood-filled bulge on a brain artery that can rupture and cause fatal bleeds—can also lead [...]
Anita Saraf investigates mosquito saliva to understand how viruses like dengue and West Nile are transmitted, using mass spectrometry to identify potential targets for vaccines and treatments. You might guess it’d be tough to extract saliva from a mosquito. And you’d be correct. Yet, because mosquitos spread disease via saliva, it’s critical to sample [...]
Nanomedicine, a branch of nanotechnology, is revolutionizing healthcare by enabling the manipulation of materials at the nanoscale to diagnose, treat, and prevent diseases. Unlike traditional treatments, nanoparticles (NPs) are highly precise in targeting diseased cells at the molecular level, enhancing the effectiveness of treatments for conditions like cancer, diabetes, infectious diseases, chronic pain, and [...]
