Stress granules play a crucial role in the stress response, arising from the aggregation of non-translating mRNAs and proteins. Although significant knowledge exists about stress granules, the mechanisms behind their mRNA localization remain partially understood. Alterations to mRNA can change the characteristics of the nucleobases, influencing key processes like translation, splicing, and the positioning [...]
Many vaccines, including vaccines for hepatitis B and whooping cough, consist of fragments of viral or bacterial proteins. These vaccines often include other molecules called adjuvants, which help to boost the immune system's response to the protein. Most of these adjuvants consist of aluminum salts or other molecules that provoke a nonspecific immune response. [...]
A novel architecture for optical neural networks utilizes wavefront shaping to precisely manipulate the travel of ultrashort pulses through multimode fibers, enabling nonlinear optical computation. Present-day artificial intelligence systems rely on billions of adjustable parameters to accomplish complex objectives. Yet, the vast quantity of these parameters incurs significant expenses. The training and implementation of [...]
In a collaborative study, researchers from Kyushu University and Harvard Medical School have identified proteins that can turn or “reprogram” fibroblasts — the most commonly found cells in skin and connective tissue — into cells with similar properties to limb progenitor cells. Publishing in Developmental Cell ("Direct reprogramming of non-limb fibroblasts to cells with [...]
Artificial Intelligence has helped scientists reveal a new form of aggressive prostate cancer, which could revolutionise how the disease is diagnosed and treated in the future. A Cancer Research UK-funded study, published in Cell Genomics, has revealed that prostate cancer, which affects one in eight men in their lifetime, includes two different subtypes termed evotypes. The discovery [...]
Recent research conducted by the University of Oxford has found that a high proportion of SARS-CoV-2 infections in the general population lead to persistent infections lasting a month or more. The findings have been published in the journal Nature. It has long been thought that prolonged COVID-19 infections in immunocompromised individuals may have been the source of the multiple new variants [...]
The human brain has billions of neurons. Working together, they enable higher-order brain functions such as cognition and complex behaviors. To study these higher-order brain functions, it is important to understand how neural activity is coordinated across various brain regions. Although techniques such as functional magnetic resonance imaging (fMRI) are able to provide insights into brain [...]
Scientists at Scripps Research identified antibodies that protect against a host of lethal snake venoms. Scripps Research scientists have developed an antibody that can block the effects of lethal toxins in the venoms of a wide variety of snakes found throughout Africa, Asia and Australia. The antibody, which protected mice from the normally deadly [...]
The human brain could be far more powerful than we ever imagined, scientists have discovered. Researchers have identified cell messaging which have never been uncovered before, which suggests our brains are capable of more than previously realised. It’s all to do with the outer cortical cells, with the findings suggesting that single human neurons are remarkably powerful. The [...]
A study from the University of California, Davis, and the National Institute of Agricultural Technology (INTA) in Argentina reveals that the highly contagious H5N1 avian influenza virus has evolved to transmit among birds and marine mammals, presenting a direct risk to wildlife conservation efforts. The study, published in the journal Emerging Infectious Diseases, is the first genomic characterization [...]
