Researchers have discovered the process by which dietary choline crosses the blood-brain barrier. This breakthrough has potential applications in enhancing drug delivery to the brain for treating neurological disorders. A researcher from the University of Queensland has identified molecular doorways that could facilitate the delivery of drugs to the brain for treating neurological disorders. Dr. Rosemary [...]

Nucleic acid-based medications such as mRNA vaccines offer tremendous potential for medicine and are opening up new therapeutic approaches. These active ingredients must be enclosed inside nanoparticles to ensure that they get to where they are needed inside the body's cells. The Fraunhofer Institute for Production Systems and Design Technology IPK and FDX Fluid [...]

By providing plausible label maps for one medical image, the Tyche machine-learning model could help clinicians and researchers capture crucial information. In biomedicine, segmentation involves annotating pixels from an important structure in a medical image, like an organ or cell. Artificial intelligence models can help clinicians by highlighting pixels that may show signs of [...]

MoTrPAC examined the molecular effects of exercise on 2,600 volunteers, incorporating factors like age, race, and gender diversity. Building upon research in rats, MoTrPAC discovered over 35,000 biological molecules responding to endurance exercise and widespread gender differences in responses. Initial findings from MoTrPAC underscore the importance of including both sexes in exercise research to [...]

A study in JAMA Oncology reveals that MyProstateScore 2.0, a new urine test analyzing 18 genes, surpasses PSA in detecting significant prostate cancers and could reduce unnecessary biopsies by up to 42%. A new urine test that measures 18 genes associated with prostate cancer provides higher accuracy for detecting clinically significant cancers than PSA and other existing biomarker [...]

This uncommon process is more frequently observed in neurodegenerative diseases and could offer insights into disease mechanisms. According to a new study published in PLOS Biology by Kim Hai-Man Chow and colleagues from the Chinese University of Hong Kong, neurons in the brain that re-enter the cell cycle after mitosis are prone to quick senescence, a [...]

Researchers at UC San Diego have utilized advanced imaging techniques to explore the metabolic processes behind Alzheimer’s disease, leading to potential new strategies for treatment. Alzheimer’s disease, the most common type of dementia, significantly impairs memory, thinking, and behavior, affecting over 50 million people globally each year. Projections suggest that this number will triple by [...]

Scientists have discovered a method to super-charge the ‘engine’ of sustainable fuel generation – by giving the materials a little twist. The researchers, led by the University of Cambridge, are developing low-cost light-harvesting semiconductors that power devices for converting water into clean hydrogen fuel, using just the power of the sun. These semiconducting materials, known as copper [...]

Blessed thistle (Cnicus benedictus), a member of the Asteraceae family, thrives in our climate. This plant has been utilized for centuries as a medicinal herb, often consumed as an extract or tea to support the digestive system. Recently, researchers at the Center for Pharmacology of University Hospital Cologne and the Faculty of Medicine of [...]

Imagine being able to look inside a single cancer cell and see how it communicates with its neighbors. Scientists are celebrating a new technique that lets them study the fatty contents of cancer cells, one by one. A study led by the University of Surrey has sampled single live cancer cells and measured the fatty lipid [...]