Artificial intelligence can predict on- and off-target activity of CRISPR tools that target RNA instead of DNA, according to new research published in Nature Biotechnology. The study by researchers at New York University, Columbia University, and the New York Genome Center, combines a deep learning model with CRISPR screens to control the expression of human genes in different [...]
Artificial intelligence facilitates the visualization of neural connections in the brains of mice. Scientists from Johns Hopkins have leveraged artificial intelligence to create a technique that allows for the visualization and monitoring of alterations in the strength of synapses — the connection points through which nerve cells in the brain communicate — in living [...]
New research indicates that cannabis may alleviate “chemo brain.” New research from the University of Colorado Boulder reveals that cancer patients employing cannabis to manage their symptoms not only experience reduced pain and enhanced sleep quality, but also enjoy another unexpected advantage: after several weeks of continuous use, they seem to think more clearly. “When you’re [...]
“Listen, if there’s one thing the history of evolution has taught us is that life will not be contained. Life breaks free. It expands to new territories, and it crashes through barriers painfully, maybe even dangerously, but . . . life finds a way,” said Ian Malcolm, Jeff Goldblum’s character in Jurassic Park, the 1993 [...]
Florida State University scientists have developed a mathematical model, explaining the growth, pattern formation, and self-healing properties of chemical gardens. These insights could lead to the development of self-repairing materials. Since the mid-1600s, chemists have been fascinated with brightly colored, coral-like structures that form by mixing metal salts in a small bottle. Until now, researchers [...]
A group led by researchers at Nagoya University in Japan has developed a technology to capture and release cell-free DNA (cfDNA) on nanowire surfaces from urine. By extracting this DNA, they were able to successfully detect IDH1 mutation, a characteristic genetic mutation of gliomas, a type of brain tumor. Their findings increase the effectiveness [...]
Researchers have developed an artificial intelligence model, TIGER, that predicts the on- and off-target activity of RNA-targeting CRISPR tools. This innovation, detailed in a study published in Nature Biotechnology, can accurately design guide RNAs, modulate gene expression, and is poised to drive advancements in CRISPR-based therapies. Artificial intelligence can predict on- and off-target activity of [...]
Scientists have illuminated the process by which a highly infectious virus, recently transmitted from animals to humans, gains entry into human cells. Dr. Ariel Isaacs and Dr. Yu Shang Low, from The University of Queensland, have successfully revealed the structure of the fusion protein of the Langya virus. This virus was first identified in humans [...]
Alzheimer’s disease, an irreversible form of dementia, is considered the world’s most common neurodegenerative disease. The prime risk factor for Alzheimer’s is age, although it remains unclear why. It is known that the insulating layer around nerve cells in the brain, named myelin, degenerates with age. Researchers at the Max Planck Institute (MPI) for Multidisciplinary Sciences [...]
A study of more than 22,000 people with multiple sclerosis (MS) has for the first time identified a genetic variant associated with faster progression of the disease, an accumulation of disability that can rob patients of their mobility and independence over time. Multiple sclerosis begins as an autoimmune disease where the immune system attacks [...]
