What determines whether an individual will develop Alzheimer’s disease, and why do many with the disease’s characteristic toxic amyloid accumulations in the brain never exhibit associated dementia symptoms? These perplexing questions have long puzzled researchers. Scientists from the University of Pittsburgh School of Medicine seem to have unveiled the answer. According to their groundbreaking research published in Nature Medicine, [...]
A study, involving the London School of Hygiene & Tropical Medicine (LSHTM) researchers, has shown that tranexamic acid (TXA), a drug aimed at tackling serious postpartum bleeding, can be safely administered intramuscularly to pregnant women, quickly achieving effective therapeutic levels. These results, derived from the Woman-PharmacoTXA Phase 2 trial, underscore the potential of using intramuscular injection [...]
Researchers from The University of Queensland have made a dust from baker's yeast that can detect COVID-19 and could safeguard communities against future pandemics. The powdery "nanoprobes" developed at UQ's Australian Institute for Bioengineering and Nanotechnology (AIBN) are synthetic yeast fragments which can be deployed in environments such as airports, hospitals, stadiums and sewers [...]
A new research has revealed a possible connection between human brain and cosmos on a quantum scale. Introduction: Connection between human brain and cosmos The human brain, with its intricate networks of neurons, has long been a subject of fascination and mystery. Concurrently, the cosmos, with its vastness and complexity, has intrigued scientists and [...]
When we breathe, the SARS-CoV-2 virus enters the body through the cells of the upper respiratory tract. Sensing an invader, the epithelial cells, which are the first line of defense, mount an immediate and broad "innate" defense and trigger an alarm. The immune system then launches a cascade of vigorous, targeted attacks. Understanding how these [...]
Brain waves act as carriers of information. A recently proposed “Cytoelectric Coupling” hypothesis suggests that these wavering electric fields contribute to the optimization of the brain network’s efficiency and robustness. They do this by influencing the physical configuration of the brain’s molecular framework. In order to carry out its multifaceted functions, which include thought, [...]
Summary: Researchers developed a single-chip device that mimics the human eye’s capacity to capture, process, and store visual data. This groundbreaking innovation, fueled by a thin layer of doped indium oxide, could be a significant leap towards applications like self-driving cars that require quick, complex decision-making abilities. Unlike traditional systems that need external, energy-intensive [...]
A new study reveals regulators of genetic activity that are linked to the immune response against COVID-19. Alterations in their expression during the initial stages of infection are associated with blood traits underlying COVID-19 severity. A group of scientists from NYU Abu Dhabi, under the leadership of Associate Professor of Biology, Youssef Idaghdour, collaborated with medical [...]
Research led by the University of Pennsylvania, Philadelphia, has used siRNA-based silencing of protein cyclophilin A (CyPA) to reduce tumor burden and extend the lives of patients with multiple myeloma. In the paper, "In vivo bone marrow microenvironment siRNA delivery using lipid–polymer nanoparticles for multiple myeloma therapy," published in PNAS, the researchers detail a targeted nanoparticle platform [...]
A new study reveals that the SARS-CoV-2 virus infects cells by binding a single virus to a single ACE2 receptor, contrary to previous theories. This was discovered through super-resolution microscopy which also showed a low density of ACE2 receptors on cell membranes, challenging the possibility of a virus particle binding to multiple receptors simultaneously. This new understanding [...]
