MIT researchers develop “FrameDiff,” a computational tool that uses generative AI to craft new protein structures, with the aim of accelerating drug development and improving gene therapy. MIT’s CSAIL researchers have developed a computational tool, FrameDiff, which employs generative AI to create new protein structures. It uses machine learning to model protein “backbones” and adjust them in [...]
Scientists have created a “living digital camera” that captures and stores images in DNA, the genetic code of all living things, reports a new study. The technique offers a novel approach to encoding digital information into biological material, an endeavor that has a host of potential future applications in computing and nanotechnology. DNA, which [...]
Artificial intelligence can predict on- and off-target activity of CRISPR tools that target RNA instead of DNA, according to new research published in Nature Biotechnology. The study by researchers at New York University, Columbia University, and the New York Genome Center, combines a deep learning model with CRISPR screens to control the expression of human genes in different [...]
Artificial intelligence facilitates the visualization of neural connections in the brains of mice. Scientists from Johns Hopkins have leveraged artificial intelligence to create a technique that allows for the visualization and monitoring of alterations in the strength of synapses — the connection points through which nerve cells in the brain communicate — in living [...]
New research indicates that cannabis may alleviate “chemo brain.” New research from the University of Colorado Boulder reveals that cancer patients employing cannabis to manage their symptoms not only experience reduced pain and enhanced sleep quality, but also enjoy another unexpected advantage: after several weeks of continuous use, they seem to think more clearly. “When you’re [...]
“Listen, if there’s one thing the history of evolution has taught us is that life will not be contained. Life breaks free. It expands to new territories, and it crashes through barriers painfully, maybe even dangerously, but . . . life finds a way,” said Ian Malcolm, Jeff Goldblum’s character in Jurassic Park, the 1993 [...]
Florida State University scientists have developed a mathematical model, explaining the growth, pattern formation, and self-healing properties of chemical gardens. These insights could lead to the development of self-repairing materials. Since the mid-1600s, chemists have been fascinated with brightly colored, coral-like structures that form by mixing metal salts in a small bottle. Until now, researchers [...]
A group led by researchers at Nagoya University in Japan has developed a technology to capture and release cell-free DNA (cfDNA) on nanowire surfaces from urine. By extracting this DNA, they were able to successfully detect IDH1 mutation, a characteristic genetic mutation of gliomas, a type of brain tumor. Their findings increase the effectiveness [...]
Researchers have developed an artificial intelligence model, TIGER, that predicts the on- and off-target activity of RNA-targeting CRISPR tools. This innovation, detailed in a study published in Nature Biotechnology, can accurately design guide RNAs, modulate gene expression, and is poised to drive advancements in CRISPR-based therapies. Artificial intelligence can predict on- and off-target activity of [...]
Scientists have illuminated the process by which a highly infectious virus, recently transmitted from animals to humans, gains entry into human cells. Dr. Ariel Isaacs and Dr. Yu Shang Low, from The University of Queensland, have successfully revealed the structure of the fusion protein of the Langya virus. This virus was first identified in humans [...]
