Molecular modeling suggests structural consequences of an early protein mutation that promoted viral transmission. RIKEN researchers discovered that an early mutation (D614G) in the SARS-CoV-2 virus may have contributed to its rapid spread by altering the spike protein’s shape, improving the virus’s ability to adapt to human hosts. The finding could help inform the development of next-generation [...]
A novel type of protein nanoparticle vaccine formulation containing influenza proteins and adjuvant to boost immune responses has provided complete protection against influenza viral challenges, according to a new study published by researchers in the Institute for Biomedical Sciences at Georgia State University. The findings published in the journal Small describe a promising influenza vaccine [...]
A NIH study on twelve Long COVID patients found differences in immune cell profiles and autonomic dysfunction, contributing to the understanding of the condition and potentially leading to better diagnoses and new treatments. Twelve people with persistent neurological symptoms after SARS-CoV-2 infection were intensely studied at the National Institutes of Health (NIH) and were found to have differences [...]
Using mRNA tailored to each patient’s tumor, the vaccine may have staved off the return of one of the deadliest forms of cancer in half of those who received it. Five years ago, a small group of cancer scientists meeting at a restaurant in a deconsecrated church hospital in Mainz, Germany, drew up an [...]
University of Minnesota Twin Cities researchers have developed a groundbreaking new diagnostic technique that will allow for faster and more accurate detection of neurodegenerative diseases. The method will likely open a door for earlier treatment and mitigation of various diseases that affect humans, such as Alzheimer's and Parkinson's, and similar diseases that affect animals, [...]
MIT engineers have designed a new nanoparticle sensor that could enable early diagnosis of cancer with a simple urine test. The sensors, which can detect many different cancerous proteins, could also be used to distinguish the type of a tumor or how it is responding to treatment. The nanoparticles are designed so that when they encounter [...]
Jean-Yves Duclos, Minister of Health, and Harjit S. Sajjan, Minister of International Development and Minister responsible for the Pacific Economic Development Agency of Canada, have recently announced an investment of over CA$100 million to support the Coalition for Epidemic Preparedness Innovations (CEPI). Through this investment, Global Affairs Canada is providing CA$100 million to support [...]
Secondary bacterial infection of the lung (pneumonia) was extremely common in patients with COVID-19, affecting almost half the patients who required support from mechanical ventilation. By applying machine learning to medical record data, scientists at Northwestern University Feinberg School of Medicine found that secondary bacterial pneumonia that does not resolve was a key driver [...]
An artificial intelligence system enables robots to conduct autonomous scientific experiments—as many as 10,000 per day—potentially driving a drastic leap forward in the pace of discovery in areas from medicine to agriculture to environmental science. That artificial intelligence platform, dubbed BacterAI, mapped the metabolism of two microbes associated with oral health—with no baseline information to start with. Bacteria [...]
Scientists have created a bacterium that is resistant to all viruses. Using strands of RNA, researchers re-coded the organism so that when viruses try to invade, their replication instructions get all mixed around. The team hopes their new tech will eventually be used to create virus-resistant bacteria to be used in producing things like [...]
