Despite the end of the pandemic, COVID-19 continues to pose a serious health threat. Most individuals have established robust immune protection and do not develop severe disease but the infection can still lead to marked and sometimes long-lasting disease symptoms. In the late summer of 2023 a new SARS-CoV-2 variant emerged, BA.2.86 (pirola), which, [...]
Unlocking the secrets of COVID-19: a groundbreaking study reveals the intricate biomechanics behind the virus’s evolution and spread. Richard Feynman famously stated, “Everything that living things do can be understood in terms of the jigglings and wigglings of atoms.” This week, Nature Nanotechnology features a groundbreaking study that sheds new light on the evolution of the coronavirus and [...]
Marla Kott was diagnosed with Stage 4 lung cancer on Nov. 21, 2014. It was her 60th birthday. "It was not a great day," said Kott, who was was one of thousands of people in Canada diagnosed with lung cancer that year. The disease accounts for a quarter of cancer deaths, according to the Canadian Cancer [...]
In 2023, AI policy and regulation went from a niche, nerdy topic to front-page news. This is partly thanks to OpenAI’s ChatGPT, which helped AI go mainstream, but which also exposed people to how AI systems work—and don’t work. It has been a monumental year for policy: we saw the first sweeping AI law [...]
Using a new technology developed at MIT, diagnosing lung cancer could become as easy as inhaling nanoparticle sensors and then taking a urine test that reveals whether a tumor is present. The new diagnostic is based on nanosensors that can be delivered by an inhaler or a nebulizer. If the sensors encounter cancer-linked proteins [...]
The blood-brain barrier blocks the entry of antibodies into the brain. This limits the potential use of antibody therapeutics to treat brain diseases, such as brain tumors. Elsewhere in the body, more than 100 United States Food and Drug Administration-approved therapeutic antibodies are used by medical teams to treat cancers and autoimmune, infectious and [...]
Researchers have created ‘nanomachines’ that use mechanical molecular motions to enter and destroy cells. Cancer is a condition where some of the body’s cells grow out of control and spread to other bodily regions. Cancer cells divide continually, leading them to invade surrounding tissue and form solid tumors. The majority of cancer treatments involve [...]
Explaining the behavior of trained neural networks remains a compelling puzzle, especially as these models grow in size and sophistication. Like other scientific challenges throughout history, reverse-engineering how artificial intelligence systems work requires a substantial amount of experimentation: making hypotheses, intervening on behavior, and even dissecting large networks to examine individual neurons. To date, [...]
In the past four years, the pathogen responsible for Coronavirus Disease 2019 (COVID-19), SARS-CoV-2, has infected more than 770 million people and caused more than 6.9 million deaths worldwide. The severe impact of SARS-CoV-2 is often attributed to its ability to suppress the interferon (IFN) response while simultaneously inducing the production of various cytokines. [...]
Researchers at the University of Bonn examine the inner workings of machine learning applications in drug research. Artificial intelligence (AI) has been advancing rapidly, but its inner workings often remain obscure, characterized by a “black box” nature where the process of reaching conclusions is not visible. However, a significant breakthrough has been made by [...]
