When we breathe, the SARS-CoV-2 virus enters the body through the cells of the upper respiratory tract. Sensing an invader, the epithelial cells, which are the first line of defense, mount an immediate and broad "innate" defense and trigger an alarm. The immune system then launches a cascade of vigorous, targeted attacks. Understanding how these [...]
Brain waves act as carriers of information. A recently proposed “Cytoelectric Coupling” hypothesis suggests that these wavering electric fields contribute to the optimization of the brain network’s efficiency and robustness. They do this by influencing the physical configuration of the brain’s molecular framework. In order to carry out its multifaceted functions, which include thought, [...]
Summary: Researchers developed a single-chip device that mimics the human eye’s capacity to capture, process, and store visual data. This groundbreaking innovation, fueled by a thin layer of doped indium oxide, could be a significant leap towards applications like self-driving cars that require quick, complex decision-making abilities. Unlike traditional systems that need external, energy-intensive [...]
A new study reveals regulators of genetic activity that are linked to the immune response against COVID-19. Alterations in their expression during the initial stages of infection are associated with blood traits underlying COVID-19 severity. A group of scientists from NYU Abu Dhabi, under the leadership of Associate Professor of Biology, Youssef Idaghdour, collaborated with medical [...]
Research led by the University of Pennsylvania, Philadelphia, has used siRNA-based silencing of protein cyclophilin A (CyPA) to reduce tumor burden and extend the lives of patients with multiple myeloma. In the paper, "In vivo bone marrow microenvironment siRNA delivery using lipid–polymer nanoparticles for multiple myeloma therapy," published in PNAS, the researchers detail a targeted nanoparticle platform [...]
A new study reveals that the SARS-CoV-2 virus infects cells by binding a single virus to a single ACE2 receptor, contrary to previous theories. This was discovered through super-resolution microscopy which also showed a low density of ACE2 receptors on cell membranes, challenging the possibility of a virus particle binding to multiple receptors simultaneously. This new understanding [...]
Multiple myeloma is an incurable bone marrow cancer that kills over 100,000 people every year. Known for its quick and deadly spread, this disease is one of the most challenging to address. As these cancer cells move through different parts of the body, they mutate, outpacing possible treatments. People diagnosed with severe multiple myeloma [...]
In a collaboration with Groningen University, Professor Jørgen Kjems and his research group at Aarhus University have achieved a remarkable breakthrough in developing tiny nano-sized pores that can contribute to better possibilities for, among other things, detecting diseases at an earlier stage. Their work, recently published in the scientific journal ACS Nano ("Specific Detection of Proteins [...]
A new study led by researchers at the University of Oxford’s Department of Computer Science has found that, between 2021 and 2022, COVID-19 was a leading cause of death in children and young people in the United States, ranking eighth overall. The results demonstrate that pharmaceutical and public health interventions should continue to be applied to [...]
A groundbreaking machine-learning study has unmasked the best drug combinations to prevent COVID-19 from coming back after an initial infection. It turns out these combos are not the same for every patient. Using real-world data from a hospital in China, the UC Riverside-led study found that individual characteristics, including age, weight, and additional illness [...]
