A group of scientists collaborated to release comprehensive structures of the entire human opioid receptor family, with the aim of facilitating the development of more precise pain medications. In an ongoing endeavor to enhance opioid pain medications, scientists from the United States and China utilized cryoEM technology to determine the comprehensive structures of the [...]
A research team from Johns Hopkins Medicine and Johns Hopkins University has developed a machine-learning (ML) tool capable of predicting who has the highest probability of being naturally resistant to COVID-19 infection despite being exposed to SARS-CoV-2, the virus that causes it. The study, published this week in PLOS One, aims to better understand the factors that influence [...]
In mouse studies, the drug was found to delay the growth of tumors and enhance the sensitivity of glioblastoma cells to anticancer treatments. Due to its highly aggressive and lethal nature, glioblastoma, a type of brain cancer, is often resistant to traditional treatments. As a result, researchers are seeking out characteristics of glioblastoma cells [...]
Developed for gastrointestinal inflammation therapy... Micro/nanorobots with self-propelling and self-navigating capabilities have attracted extensive attention in from researchers in drug delivery and therapy due to their controllable locomotion in hard-to-reach body tissues. However, developing self-adaptive micro/nanorobots that can adjust their driving mechanisms across multiple biological barriers to reach distant lesions is still a challenge. [...]
In a new breakthrough, researchers at the University of Copenhagen, in collaboration with Ruhr University Bochum, have solved a problem that has caused quantum researchers headaches for years. The researchers can now control two quantum light sources rather than one. Trivial as it may seem to those uninitiated in quantum, this colossal breakthrough allows [...]
Some researchers are driven by the quest to improve a specific product, like a battery or a semiconductor. Others are motivated by tackling questions faced by a given industry. Rob Macfarlane, MIT’s Paul M. Cook Associate Professor in Materials Science and Engineering, is driven by a more fundamental desire. “I like to make things,” [...]
Matt Fitzgerald used to bike up and down 3,500 feet through the Santa Ana Mountains on three-hour rides just for fun. Now, nine months after being infected with SARS-CoV-2, the virus that causes Covid-19, he can’t muster walking on flat surfaces for 20 minutes without days of exhaustion. “My long Covid life remains terrifying,” [...]
Up to now, the use of models to research the barrier that separates the circulatory from the nervous system has proven to be either limited or extremely complicated. Researchers at ETH Zurich have developed a more realistic model that can also be used to better explore new treatments for brain tumours. Mario Modena is [...]
A Hamburg-based research team has developed a new method for producing a network of large to very fine pores in silicon and glass. At DESY’s X-ray source PETRA III, scientists led by DESY researchers Stella Gries and Patrick Huber were able to analyse the porosity using X-ray tomography. The method for producing micro- and [...]
Recently, researchers at Yale University and the University of Connecticut collaborated to develop a nanoparticle-based treatment to fight glioblastoma (GBM), one of the most harmful malignancies with a high recurrence rate and poor clinical outcome. This newly developed technique targets multiple factors associated with GBM progression and invasiveness. The findings were published in Science Advances. [...]
