New findings raise questions about the role of microbes living in the lungs. More than 35 trillion bacteria live throughout the human body, forming microbiomes in the gut, mouth, lungs, skin, and urogenital tract. Researchers increasingly recognize that these microbial communities are connected to both health and disease, but much about what individual microbes [...]
From the preface of the book Global Health Care Equivalency in the Age of Nanotechnology, Nanomedicine and Artificial Intelligence, Edited by Frank Boehm: Since the publication of my first book (Nanomedical Device and Systems Design: Challenges, Possibilities, Visions – CRC Press, 2013), it became increasingly evident that synergies between the concurrently rapid advances in [...]
Pelacarsen didn’t protect heart health despite lowering levels of a protein particle, “Lp(a),” in a large clinical trial — a result with important implications for cardiovascular drug research. Dive Brief: An RNA drug from Novartis and Ionis Pharmaceuticals failed to reduce the risk of heart attacks, strokes and death in a clinical trial, an outcome [...]
Biomedical engineers at Duke University have created an injectable biomaterial that may help the brain recover from damage left behind by an ischemic stroke. In experiments with mice, the material transformed the cavity created by lost brain tissue into a more favorable environment for healing. The treatment recruited the body's own immune cells, encouraged [...]
Researchers discovered lymph node-like immune hubs inside skull bone marrow that appear to act as rapid-response centers for the brain. For decades, the brain was thought to operate largely apart from the immune system. Researchers at Washington University School of Medicine in St. Louis have now identified lymph node-like structures inside the skull bone marrow of [...]
Researchers have developed a potential new approach for treating a form of cystic fibrosis caused by so-called nonsense mutations, combining chemically modified transfer RNAs with lipid nanoparticles designed to deliver the therapy directly to the lungs. The study, led by Jingan Chen and colleagues, found that the treatment restored production of functional cystic fibrosis [...]
A groundbreaking treatment for one of the most common forms of pancreatic cancer has been approved in pill form by the FDA. Revolution Medicines’ oral tablet daraxonrasib, branded as Rasonque, reduced the risk of death by 60% in phase 3 trials. Patients who received the medication in trials lived 13.2 months, compared with those [...]
A cancer-linked protein called BRAF may help drive chronic nerve pain, and existing cancer drugs targeting it reduced pain sensitivity in preclinical models. Chronic nerve pain can persist long after an injury and often responds poorly to standard pain medications. Researchers at The University of Texas MD Anderson Cancer Center now report evidence that [...]
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Introduction Healthcare is approaching a frontier where the quantum portfolio could influence not only how disease is diagnosed and treated, but how health itself is measured, modeled, predicted and preserved. Quantum computing, quantum simulation, quantum sensing, quantum communications and post-quantum cryptography could become increasingly important components of the computational and security infrastructure supporting wellness, [...]
