The CIC biomaGUNE Center for Cooperative Research in Biomaterials has developed pulmonary surfactant nanoparticles (the blend of lipids and proteins that line the alveoli and enables breathing), which are encapsulated in a drug used to treat pulmonary fibrosis. The researchers show that these nanoparticles are highly capable of remaining trapped [...]

PFDA, a PFAS “forever chemical,” can cause craniofacial birth defects by disrupting retinoic acid regulation during fetal development, revealing the first clear molecular mechanism behind the link. Researchers have long linked perfluoroalkyl and polyfluoroalkyl substances (PFAS), often called “forever chemicals,” to serious birth defects. However, scientists have struggled to explain exactly how these pollutants affect fetal [...]

Leishmania parasites appear to evolve through widespread genetic exchange, reshaping assumptions about how they adapt and spread. A parasite long thought to spread mostly by cloning itself may be far more genetically dynamic than scientists once believed. A new international study suggests that Leishmania—a group of microscopic parasites responsible for debilitating tropical diseases—regularly swaps genetic [...]

Stanford researchers have developed a microscope that can show how nanostructures interact inside living cells at the highest resolution achieved so far. The view into living cells just got better. Stanford researchers have merged two microscopy methods to build a unique instrument that can capture cell structures interacting in real time at an unprecedented [...]

By Mariam Sunny and Jennifer Rigby May 29 (Reuters) – Global health authorities are racing to identify medical options to help contain an Ebola outbreak in eastern Democratic Republic of Congo, linked to the Bundibugyo strain of the virus. Unlike for the more common Zaire strain, there are no approved vaccines or treatments for [...]

A major Swiss study found that colorectal cancer is becoming increasingly common in adults under 50, even as rates decline in older age groups. Researchers in Switzerland have identified a concerning trend: while colorectal cancer rates are declining among older adults, the disease is becoming increasingly common in younger people, including some in their [...]

Researchers identified key differences between two widely used multiple sclerosis models, showing how each can better study myelin damage, immune responses, and repair. The findings may improve efforts to develop treatments that restore lost myelin. More than 1 million people in the United States are living with multiple sclerosis (MS), a disease that damages [...]

A new study reveals a possible way to make CAR T-cell therapy more durable and effective by targeting a single gene-regulating protein. CAR T-cell therapy is widely seen as a breakthrough in personalized cancer care. The treatment works by modifying a patient’s own immune cells so they can identify and attack cancer cells. Although [...]

Researchers have identified a vitamin B12–based compound that appears capable of crossing the blood–brain barrier and selectively accumulating in glioblastoma tissue. For decades, one of the biggest problems in brain cancer treatment has had little to do with killing cancer cells and everything to do with reaching them. The brain’s protective blood-brain barrier (BBB) [...]

A daily inulin supplement may help reduce knee osteoarthritis pain while revealing a possible link between gut health, muscle function, and pain sensitivity. For millions of people living with knee osteoarthritis, managing chronic pain often means choosing between medications with unwanted side effects and exercise programs that can be difficult to maintain. Now, researchers [...]