Cancer immunotherapy, which uses drugs that stimulate the body’s immune cells to attack tumors, is a promising approach to treating many types of cancer. However, it doesn’t work well for some tumors, including ovarian cancer. To elicit a better response, MIT researchers have designed new nanoparticles that can deliver an immune-stimulating molecule called IL-12 [...]

By restructuring a common chemotherapy drug, scientists increased its potency by 20,000 times. In a significant step forward for cancer therapy, researchers at Northwestern University have redesigned the molecular structure of a well-known chemotherapy drug, greatly increasing its solubility, effectiveness, and safety. For this study, the scientists created the drug entirely from scratch as a spherical [...]

Cardiovascular disease continues to be the leading cause of death worldwide. But advances in heart-failure therapeutics have stalled, largely due to the difficulty of delivering treatments at the cellular level. Now, a UC Berkeley-led team of researchers may have solved this delivery bottleneck, potentially opening the door to novel, lifesaving treatments. At the core [...]

The brain does not need its sophisticated cortex to interpret the visual world. A new study published in PLOS Biology demonstrates that a much older structure, the superior colliculus, contains the necessary circuitry to perform the fundamental computations that allow us to distinguish objects from the background and detect which stimuli are relevant in space. This [...]

Engineers have developed a passive evaporative cooling membrane that dramatically improves heat removal for electronics and data centers Engineers at the University of California San Diego have created an innovative cooling system designed to greatly enhance the energy efficiency of data centers and high-performance electronic devices. This new approach relies on a specially engineered fiber membrane [...]

In a promising advance for cancer treatment, Northwestern University scientists have re-engineered the molecular structure of a common chemotherapy drug, making it dramatically more soluble and effective and less toxic. In the new study, the team designed a new drug from the ground up as a spherical nucleic acid (SNA) — a nanostructure that [...]

A study reveals that a protein called RPA is essential for maintaining chromosome stability by stimulating telomerase. New findings from the University of Wisconsin-Madison suggest that problems with a key protein that helps preserve chromosome stability may contribute to the development of severe, and sometimes fatal, diseases. The study, published in Science, offers new clues for identifying [...]

A new nanotech-based formulation using quercetin and omega-3 fatty acids shows promise in halting bacterial biofilms and boosting skin cell repair. Scientists have developed a nanotechnology-based treatment to fight bacterial biofilms in wound infections. The study, published in Materials Today Nano, tested quercetin (Q) and omega-3 fatty acid (ω3)-loaded lipid hybrid nanoassemblies (LHNs) against bacteria Staphylococcus aureus and Escherichia [...]

While Artificial Intelligence (AI) can be a powerful tool that physicians can use to help diagnose their patients and has great potential to improve accuracy, efficiency and patient safety, it has its drawbacks. It may distract doctors, give them too much confidence in the answers it provides, and even lead them to lose confidence [...]

A comprehensive review in "Biofunct. Mater." meticulously details the most recent advancements and clinical translation of intelligent nanodrugs for breast cancer treatment. This paper presents an exhaustive overview of subtype-specific nanostrategies, the clinical benefits of FDA-approved nanodrugs, and innovative approaches to address tumor heterogeneity and treatment resistance. This serves as a foundational framework and [...]