Inflammation of the arteries is a primary precursor and driver of cardiovascular disease—the No. 1 killer of people in the United States. This inflammation is associated with the buildup of dangerous plaque inside the arteries. Advanced treatments are needed to target this inflammation in patients. Michigan State University researchers have tested a new nanoparticle [...]
A groundbreaking research effort involving teams from the University of Virginia, Mount Sinai, the University of Michigan, the University of Texas, and others has displayed the clinical efficacy of an innovative therapy that utilizes nanoparticles and laser guidance for prostate cancer treatment. The findings were published in the Journal of Urology. The research, involving 44 men with [...]
Monoclonal antibodies (mAbs) are used to prevent, detect, and treat a broad spectrum of non-communicable and communicable diseases. Over the past few years, the market for mAbs has grown exponentially with an expected compound annual growth rate (CAGR) of 11.07% from 2024 (237.64 billion USD estimated at the end of 2023) to 2033 (679.03 [...]
Researchers found that DNA mutations from antiviral enzymes and chemotherapy fuel early bladder cancer, while abnormal circular DNA in tumor cells drives resistance to therapy. These discoveries open new therapeutic avenues. A groundbreaking study led by researchers at Weill Cornell Medicine and the New York Genome Center has provided unprecedented insights into how bladder cancer begins and progresses. [...]
A recent article published in the Journal of Chemical Information and Modeling researchers at Southern Methodist University (SMU) have developed SmartCADD, an open-source virtual tool designed to speed up drug discovery. SmartCADD combines artificial intelligence, quantum mechanics, and computer-assisted drug design (CADD) techniques to screen billions of chemical compounds, [...]
Researchers at the University of Dundee have revealed in the greatest detail yet the workings of molecules called protein degraders which can be deployed to combat what have previously been regarded as "undruggable" diseases, including cancers and neurodegenerative diseases. Protein degrader molecules are heralding a revolution in drug discovery, with more than 50 drugs [...]
Largest discovery of new virus species sheds light on the hidden virosphere. Artificial intelligence (AI) has been used to reveal details of a diverse and fundamental branch of life living right under our feet and in every corner of the globe. These viruses not only play significant roles in human health but are also prevalent in extreme [...]
Research indicates that COVID-19 survivors face doubled risks of severe cardiac events for years after recovery, especially if hospitalized. People with A, B, or AB blood types are particularly vulnerable, highlighting the need for personalized approaches to heart health post-COVID. COVID-19 and Cardiovascular Risk A history of COVID-19 can double the risk of heart attack, stroke, [...]
For long periods of its history, artificial intelligence has lurked in the hinterland of science, often unloved and unfunded—but two Nobel prizes in one week suggest its time in the sunshine has finally arrived. First on Tuesday, Geoffrey Hinton and John Hopfield won the physics prize for their pioneering work in creating the foundations of modern [...]
A new study provides further evidence that consciousness depends on communication between the brain’s sensory and cognitive regions in the cortex. Our brains are constantly making predictions about our surroundings, enabling us to focus on and respond to unexpected events. A recent study explores how this predictive process functions during consciousness and how it [...]
