Public health experts are divided over how many people are getting long COVID-19, a potentially debilitating condition that comes after a patient has recovered from the coronavirus.
Ill effects from the condition can include fatigue, pain, neurological issues and even changes in mental health.
Initially, public health officials believed that only a small minority of people would suffer from long COVID-19. But some studies now indicate a majority of those infected with the coronavirus are experiencing long COVID-19 symptoms.
Still, estimates on the numbers of people with long COVID are all over the map.
Researchers from the Penn State College of Medicine found that more than half of COVID-19 survivors had long COVID-19.
Another study from the University of Arizona found that about 2 out of 3 people who experienced mild or moderate cases of coronavirus had long-lasting symptoms.
Other reports have been more conservative, estimating anywhere between 10 to 30 percent of those infected develop long-term symptoms. Those who experience ongoing symptoms from long COVID-19 have sometimes come to be known as COVID-19 long haulers.
One problem in figuring out how many people get long COVID-19 is defining it.
Apart from the wide range of symptoms, there is still debate over when a person is considered to have long COVID-19. Some health care authorities consider a patient to have the condition if symptoms persist after three to six weeks, while other think it should be considered on a longer basis.
Jim Heath, president and professor at the Institute for Systems Biology, is leading the Pacific Northwest consortium researching long COVID-19 as part of the National Institute of Health’s (NIH) RECOVER initiative, which is looking into the post-COVID-19 condition and potential ways of preventing and treating it.
Heath told The Hill that if one definition of long COVID-19 was being used — one in which symptoms lingered about four to six weeks after infection — then roughly half of those infected would be considered to have long COVID-19.
According to Heath, an estimate of 15 to 20 percent of coronavirus survivors experiencing long COVID-19 after six months was a reasonable “educated guess” and he added that there was evidence to support that rate of occurrence.
When reached for comment by The Hill, the NIH said initial studies have found that at least half of COVID-19 patients who were hospitalized reported “persistent weakness or fatigue” months after their recovery.
Studies on the prevalence of long COVID-19 have been “relatively few,” according to the NIH, and they have all focused on people who had symptomatic cases of COVID-19.
The NIH said numerous observational studies in both children and adults are being conducted to find potential treatments for long haulers. The agency has requested applications for new clinical trials to launch this summer to test potential ways of preventing and treating long COVID-19.
“In contrast to the wealth of prior knowledge that led to the vaccines for Sars-CoV-2 and a host of other viruses, there is much less known about what causes persistent symptoms following infectious illnesses or how to best treat them. As a consequence, there is more knowledge needed to fuel the scientific advances to come,” the NIH said.

News
Team finds flawed data in recent study relevant to coronavirus antiviral development
The COVID pandemic illustrated how urgently we need antiviral medications capable of treating coronavirus infections. To aid this effort, researchers quickly homed in on part of SARS-CoV-2's molecular structure known as the NiRAN domain—an [...]
Drug-Coated Neural Implants Reduce Immune Rejection
Summary: A new study shows that coating neural prosthetic implants with the anti-inflammatory drug dexamethasone helps reduce the body’s immune response and scar tissue formation. This strategy enhances the long-term performance and stability of electrodes [...]
Scientists discover cancer-fighting bacteria that ‘soak up’ forever chemicals in the body
A family of healthy bacteria may help 'soak up' toxic forever chemicals in the body, warding off their cancerous effects. Forever chemicals, also known as PFAS (per- and polyfluoroalkyl substances), are toxic chemicals that [...]
Johns Hopkins Researchers Uncover a New Way To Kill Cancer Cells
A new study reveals that blocking ribosomal RNA production rewires cancer cell behavior and could help treat genetically unstable tumors. Researchers at the Johns Hopkins Kimmel Cancer Center and the Department of Radiation Oncology and Molecular [...]
AI matches doctors in mapping lung tumors for radiation therapy
In radiation therapy, precision can save lives. Oncologists must carefully map the size and location of a tumor before delivering high-dose radiation to destroy cancer cells while sparing healthy tissue. But this process, called [...]
Scientists Finally “See” Key Protein That Controls Inflammation
Researchers used advanced microscopy to uncover important protein structures. For the first time, two important protein structures in the human body are being visualized, thanks in part to cutting-edge technology at the University of [...]
AI tool detects 9 types of dementia from a single brain scan
Mayo Clinic researchers have developed a new artificial intelligence (AI) tool that helps clinicians identify brain activity patterns linked to nine types of dementia, including Alzheimer's disease, using a single, widely available scan—a transformative [...]
Is plastic packaging putting more than just food on your plate?
New research reveals that common food packaging and utensils can shed microscopic plastics into our food, prompting urgent calls for stricter testing and updated regulations to protect public health. Beyond microplastics: The analysis intentionally [...]
Aging Spreads Through the Bloodstream
Summary: New research reveals that aging isn’t just a local cellular process—it can spread throughout the body via the bloodstream. A redox-sensitive protein called ReHMGB1, secreted by senescent cells, was found to trigger aging features [...]
AI and nanomedicine find rare biomarkers for prostrate cancer and atherosclerosis
Imagine a stadium packed with 75,000 fans, all wearing green and white jerseys—except one person in a solid green shirt. Finding that person would be tough. That's how hard it is for scientists to [...]
Are Pesticides Breeding the Next Pandemic? Experts Warn of Fungal Superbugs
Fungicides used in agriculture have been linked to an increase in resistance to antifungal drugs in both humans and animals. Fungal infections are on the rise, and two UC Davis infectious disease experts, Dr. George Thompson [...]
Scientists Crack the 500-Million-Year-Old Code That Controls Your Immune System
A collaborative team from Penn Medicine and Penn Engineering has uncovered the mathematical principles behind a 500-million-year-old protein network that determines whether foreign materials are recognized as friend or foe. How does your body [...]
Team discovers how tiny parts of cells stay organized, new insights for blocking cancer growth
A team of international researchers led by scientists at City of Hope provides the most thorough account yet of an elusive target for cancer treatment. Published in Science Advances, the study suggests a complex signaling [...]
Nanomaterials in Ophthalmology: A Review
Eye diseases are becoming more common. In 2020, over 250 million people had mild vision problems, and 295 million experienced moderate to severe ocular conditions. In response, researchers are turning to nanotechnology and nanomaterials—tools that are transforming [...]
Natural Plant Extract Removes up to 90% of Microplastics From Water
Researchers found that natural polymers derived from okra and fenugreek are highly effective at removing microplastics from water. The same sticky substances that make okra slimy and give fenugreek its gel-like texture could help [...]
Instant coffee may damage your eyes, genetic study finds
A new genetic study shows that just one extra cup of instant coffee a day could significantly increase your risk of developing dry AMD, shedding fresh light on how our daily beverage choices may [...]