A case of lead poisoning due to Ayurvedic medicine use demonstrates the importance of patient history in diagnosis and the need for public health collaboration to prevent similar risks.
An article in CMAJ (Canadian Medical Association Journal) highlights a case of lead toxicity from Ayurvedic medicines in a young woman, and the complexity in diagnosing the rare condition.
“Given that lead toxicity is uncommon and its presentation nonspecific, patients are often seen by many health care providers before the diagnosis is made,” writes Dr. Julian Gitelman, Dalla Lana School of Public Health, University of Toronto, with coauthors. “A careful exposure history is essential to suggest the diagnosis.”
Ayurvedic medicine, also known as Ayurveda, is one of the world’s oldest holistic healing systems. Originating in India over 3,000 years ago, it is based on the belief that health and wellness depend on a balance between the mind, body, and spirit. Ayurveda emphasizes the importance of maintaining this balance through diet, herbal treatments, meditation, yoga, and other lifestyle practices. Its approach to health is tailored to an individual’s unique constitution or “dosha,” aiming to treat the root cause of symptoms and promote long-term well-being.
Patient Case and Diagnosis
The patient, a 39-year-old woman, visited the emergency department 3 times in 6 weeks for abdominal pain, constipation, nausea and vomiting. On her third visit, she was admitted to the hospital for anemia and possible gastrointestinal bleeding. Numerous, invasive investigations failed to reveal a cause of her symptoms.
At a follow-up visit weeks later, she reported having taken Ayurvedic medicines daily for more than a year to treat infertility. Her blood lead level was high at 55 µg/dL, compared with a normal level of less than 2 µg/dL. The patient stopped taking the Ayurvedic treatments and began chelation therapy. Her blood lead level decreased and her symptoms resolved.
Public Health Response and Investigation
Once the diagnosis of lead toxicity was made, the medical team contacted Public Health Ontario (PHO), which tested 17 different pill samples provided by the patient. After testing revealed high levels of lead in most of the pills, PHO involved the local public health unit, Toronto Public Health, and Health Canada, as it regulates natural health products. A joint investigation of the Ayurvedic clinic resulted in the seizure of hundreds of pills due to noncompliance with the Natural Health Products Regulations. Both Health Canada and Toronto Public Health issued public advisories to warn people that the products from this specific business were health hazards.
The authors emphasize the importance of communication and collaboration between clinicians and public health to minimize the health risk of lead in consumer products. “A recent systematic review of case reports on lead poisoning found traditional or herbal medications to be a common cause.” the authors write. “Heavy metals are sometimes intentionally added for their perceived healing properties.”
“When consumer products may be contaminated with lead, or when lead exposure is linked to sources in the community, involving public health can facilitate broader actions to reduce and prevent exposures to other people at risk,” they conclude.
Reference: “Lead toxicity from Ayurvedic medicines” by Julian Gitelman, Howard An, Vincent Spilchuk and JinHee Kim, 8 August 2024, Canadian Medical Association Journal.
DOI: 10.1503/cmaj.230592
News
AI Is Overheating. This New Technology Could Be the Fix
Engineers have developed a passive evaporative cooling membrane that dramatically improves heat removal for electronics and data centers Engineers at the University of California San Diego have created an innovative cooling system designed to greatly enhance [...]
New nanomedicine wipes out leukemia in animal study
In a promising advance for cancer treatment, Northwestern University scientists have re-engineered the molecular structure of a common chemotherapy drug, making it dramatically more soluble and effective and less toxic. In the new study, [...]
Mystery Solved: Scientists Find Cause for Unexplained, Deadly Diseases
A study reveals that a protein called RPA is essential for maintaining chromosome stability by stimulating telomerase. New findings from the University of Wisconsin-Madison suggest that problems with a key protein that helps preserve chromosome stability [...]
Nanotech Blocks Infection and Speed Up Chronic Wound Recovery
A new nanotech-based formulation using quercetin and omega-3 fatty acids shows promise in halting bacterial biofilms and boosting skin cell repair. Scientists have developed a nanotechnology-based treatment to fight bacterial biofilms in wound infections. The [...]
Researchers propose five key questions for effective adoption of AI in clinical practice
While Artificial Intelligence (AI) can be a powerful tool that physicians can use to help diagnose their patients and has great potential to improve accuracy, efficiency and patient safety, it has its drawbacks. It [...]
Advancements and clinical translation of intelligent nanodrugs for breast cancer treatment
A comprehensive review in "Biofunct. Mater." meticulously details the most recent advancements and clinical translation of intelligent nanodrugs for breast cancer treatment. This paper presents an exhaustive overview of subtype-specific nanostrategies, the clinical benefits [...]
It’s Not “All in Your Head”: Scientists Develop Revolutionary Blood Test for Chronic Fatigue Syndrome
A 96% accurate blood test for ME/CFS could transform diagnosis and pave the way for future long COVID detection. Researchers from the University of East Anglia and Oxford Biodynamics have created a highly accurate [...]
How Far Can the Body Go? Scientists Find the Ultimate Limit of Human Endurance
Even the most elite endurance athletes can’t outrun biology. A new study finds that humans hit a metabolic ceiling at about 2.5 times their resting energy burn. When ultra-runners take on races that last [...]
World’s Rivers “Overdosing” on Human Antibiotics, Study Finds
Researchers estimate that approximately 8,500 tons of antibiotics enter river systems each year after passing through the human body and wastewater treatment processes. Rivers spanning millions of kilometers across the globe are contaminated with [...]
Yale Scientists Solve a Century-Old Brain Wave Mystery
Yale scientists traced gamma brain waves to thalamus-cortex interactions. The discovery could reveal how brain rhythms shape perception and disease. For more than a century, scientists have observed rhythmic waves of synchronized neuronal activity [...]
Can introducing peanuts early prevent allergies? Real-world data confirms it helps
New evidence from a large U.S. primary care network shows that early peanut introduction, endorsed in 2015 and 2017 guidelines, was followed by a marked decline in clinician-diagnosed peanut and overall food allergies among [...]
Nanoparticle blueprints reveal path to smarter medicines
Lipid nanoparticles (LNPs) are the delivery vehicles of modern medicine, carrying cancer drugs, gene therapies and vaccines into cells. Until recently, many scientists assumed that all LNPs followed more or less the same blueprint, [...]
How nanomedicine and AI are teaming up to tackle neurodegenerative diseases
When I first realized the scale of the challenge posed by neurodegenerative diseases, such as Alzheimer's, Parkinson's disease and amyotrophic lateral sclerosis (ALS), I felt simultaneously humbled and motivated. These disorders are not caused [...]
Self-Organizing Light Could Transform Computing and Communications
USC engineers have demonstrated a new kind of optical device that lets light organize its own route using the principles of thermodynamics. Instead of relying on switches or digital control, the light finds its own [...]
Groundbreaking New Way of Measuring Blood Pressure Could Save Thousands of Lives
A new method that improves the accuracy of interpreting blood pressure measurements taken at the ankle could be vital for individuals who are unable to have their blood pressure measured on the arm. A newly developed [...]
Scientist tackles key roadblock for AI in drug discovery
The drug development pipeline is a costly and lengthy process. Identifying high-quality "hit" compounds—those with high potency, selectivity, and favorable metabolic properties—at the earliest stages is important for reducing cost and accelerating the path [...]
